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1

Inhibition of Severe Acute Respiratory Syndrome Coronavirus Replication in a Lethal SARS-Cov Balb/C Mouse Model by Stinging Nettle Lectin, Urtica Dioica Agglutinin (UDA)

Yohichi Kumaki, Miles K. Wandersee, Kevin W. Bailey, Aaron J. Smith, Craig W. Day, Jason R. Madson, Donald F. Smee, Dale L. Barnard

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 71 KB

english, 2010

2

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

Furuta, Yousuke, Gowen, Brian B., Takahashi, Kazumi, Shiraki, Kimiyasu, Smee, Donald F., Barnard, Dale L.

Journal:

Antiviral Research

Year:

2013

Language:

english

File:

PDF, 1.01 MB

english, 2013

3

The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses

Pécheur, Eve-Isabelle, Borisevich, Viktoriya, Halfmann, Peter, Morrey, John D., Smee, Donald F., Prichard, Mark, Mire, Chad E., Kawaoka, Yoshihiro, Geisbert, Thomas W., Polyak, Stephen J., Ou, J.-H. J

Journal:

Journal of Virology

Year:

2016

Language:

english

File:

PDF, 2.07 MB

english, 2016

4

SPIE Proceedings [SPIE SPIE Astronomical Telescopes + Instrumentation - Edinburgh, United Kingdom (Sunday 26 June 2016)] High Energy, Optical, and Infrared Detectors for Astronomy VII - Performance of science grade HgCdTe H4RG-15 image sensors

Holland, Andrew D., Beletic, James, Zandian, Majid, Farris, Mark, McLevige, William, Edwall, Dennis, Arkun, Erdem, Holland, Eric, Gunn, James E., Smee, Stephen, Hall, Donald N. B., Hodapp, Klaus W., S

Year:

2016

Language:

english

File:

PDF, 887 KB

english, 2016

5

A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo

CovÃ©s-Datson, Evelyn M., King, Steven R., Legendre, Maureen, Gupta, Auroni, Chan, Susana M., Gitlin, Emily, Kulkarni, Vikram V., PantaleÃ³n GarcÃa, Jezreel, Smee, Donald F., Lipka, Elke, Evans, Scot

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

Language:

english

File:

PDF, 1.56 MB

english, 2020

6

Synthesis and Anti-Herpetic Activity of A 2′-Fluoroarabinosyl Analog of Trifluridine

Smee, Donald F., Chernow, Marlene, Kraft, Monica, Okamoto, Patricia M., Prisbe, Ernest J.

Journal:

Nucleosides and Nucleotides

Year:

1988

Language:

english

File:

PDF, 432 KB

english, 1988

7

T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections

Yousuke Furuta, Kazumi Takahashi, Kimiyasu Shiraki, Kenichi Sakamoto, Donald F. Smee, Dale L. Barnard, Brian B. Gowen, Justin G. Julander, John D. Morrey

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 672 KB

english, 2009

8

Synthesis and Biological Evaluation of Epidithio-, Epitetrathio-, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8′- epi - ent -Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents

Nicolaou, K. C., Lu, Min, Totokotsopoulos, Sotirios, Heretsch, Philipp, Giguère, Denis, Sun, Ya-Ping, Sarlah, David, Nguyen, Thu H., Wolf, Ian C., Smee, Donald F., Day, Craig W., Bopp, Selina, Winzele

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 3.20 MB

english, 2012

9

Use of plethysmography in assessing the efficacy of antivirals in a mouse model of pandemic influenza A virus

Justin G. Julander, Joe Hagloch, Scott Latimer, Neil Motter, Ashley Dagley, Dale L. Barnard, Donald F. Smee, John D. Morrey

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

10

9-(1,3-Dihydroxy-2-propoxymethyl)guanine: a new potent and selective antiherpes agent

Martin, John C., Dvorak, Charles A., Smee, Donald F., Matthews, Thomas R., Verheyden, Julien P. H.

Journal:

Journal of Medicinal Chemistry

Year:

1983

Language:

english

File:

PDF, 406 KB

english, 1983

11

Synthesis and biological properties of purine and pyrimidine 5'-deoxy-5'-(dihydroxyphosphinyl)-.beta.-D-ribofuranosyl analogs of AMP, GMP, IMP, and CMP

Raju, Natarajan, Smee, Donald F., Robins, Roland K., Vaghefi, Morteza M.

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 1.00 MB

english, 1989

12

The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice

Warfield, Kelly, Barnard, Dale, Enterlein, Sven, Smee, Donald, Khaliq, Mansoora, Sampath, Aruna, Callahan, Michael, Ramstedt, Urban, Day, Craig

Journal:

Year:

2016

Language:

english

File:

PDF, 770 KB

english, 2016

13

In vitro and in vivo assay systems for study of influenza virus inhibitors

Robert W. Sidwell, Donald F. Smee

Journal:

Antiviral Research

Year:

2000

Language:

english

File:

PDF, 133 KB

english, 2000

14

A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo

Craig W. Day, Ralph Baric, Sui Xiong Cai, Matt Frieman, Yohichi Kumaki, John D. Morrey, Donald F. Smee, Dale L. Barnard

Journal:

Year:

2009

Language:

english

File:

PDF, 1.28 MB

english, 2009

15

C3H/HeN mouse model for the evaluation of antiviral agents for the treatment of Venezuelan equine encephalitis virus infection

Justin G. Julander, Ramona Skirpstunas, Venkatraman Siddharthan, Kristiina Shafer, Justin D. Hoopes, Donald F. Smee, John D. Morrey

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 1.92 MB

english, 2008

16

Efficacy of Combinations of Oseltamivir and Peramivir in Treating Influenza a (H1N1) Virus Infections in Cell Culture and in Mice

Donald Smee, Brett Hurst, Min-Hui Wong, E. Bart Tarbet, Y.S. Babu, John Morrey

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 65 KB

english, 2010

17

Influence of virus strain, challenge dose, and time of therapy initiation on the in vivo influenza inhibitory effects of RWJ-270201

Robert W Sidwell, Donald F Smee, John H Huffman, Dale L Barnard, John D Morrey, Kevin W Bailey, W.-C Feng, Y.S Babu, Karen Bush

Journal:

Antiviral Research

Year:

2001

Language:

english

File:

PDF, 140 KB

english, 2001

18

Antiviral activities of 2′-deoxyribofuranosyl and arabinofuranosyl analogs of sangivamycin against retro- and DNA viruses

Donald F. Smee, Patricia A. McKernan, Hassan A. Alaghamandan, Karl B. Frank, Kandasamy Ramasamy, Ganapathi R. Revankar, Roland K. Robins

Journal:

Antiviral Research

Year:

1988

Language:

english

File:

PDF, 832 KB

english, 1988

19

Inhibition of reoviruses in vitro by selected antiviral substances

Smee, Donald F., Sidwell, Robert W., Clark, Scott M., Barnett, Bill B., Spendlove, Rex S.

Journal:

Antiviral Research

Year:

1981

Language:

english

File:

PDF, 427 KB

english, 1981

20

Synthesis of Tubercidin, 6-Chlorotubercidin and Related Nucleosides

Anderson, Jack D., Bontems, Roger J., Geary, Stewart, Cottam, Howard B., Larson, Steven B., Matsumoto, Steven S., Smee, Donald F., Robins, Roland K.

Journal:

Nucleosides and Nucleotides

Year:

1989

Language:

english

File:

PDF, 752 KB

english, 1989

21

Development of a respiratory disease model for enterovirus D68 in 4-week-Old mice for evaluation of antiviral therapies

Evans, W. Joseph, Hurst, Brett L., Peterson, Christopher J., Van Wettere, Arnaud J., Day, Craig W., Smee, Donald F., Tarbet, E. Bart

Journal:

Antiviral Research

Year:

2018

Language:

english

File:

PDF, 1.90 MB

english, 2018

22

Synthesis and In Vivo antitumor and antiviral activities of 2′-deoxyribofuranosyl and arabinofuranosyl nucleosides of certain purine-6-sulfenamides, sulfinamides and sulfonamides

Ganapathi R. Revankar, Naeem B. Hanna, Kandasamy Ramasamy, Steven B. Larson, Donald F. Smee, Rick A. Finch, Thomas L. Avery, Roland K. Robins

Journal:

Journal of Heterocyclic Chemistry

Year:

1990

File:

PDF, 849 KB

1990

23

Discovery of New Inhibitors of the Influenza H5N1 Virus

William Severson, Xi Chen, Joseph Maddry, Yong-Kyu Chu, Colleen Jonsson, Alexis McBrayer, Ronald Tapp, Donald Smee, Clinton Maddox, Subramaniam Ananthan, James Noah, Leland Black, Blake Moore, Melinda

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

24

A Heterocyclic Molecule with Significant Activity Against Dengue Virus

Vasu Nair, Guochen Chi, Qingning Shu, Justin Julander, Donald Smee

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 123 KB

english, 2009

25

Antiviral Drug Efficacy Evaluation Against Pandemic Influenza a (H1N1) Viruses in MDCK Cells

Bart Tarbet, Brett Hurst, Dale Barnard, Y.S. Babu, Yousuke Furuta, Donald Smee

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 72 KB

english, 2010

26

Combinations of L-N G -monomethyl-arginine and oseltamivir against pandemic influenza A virus infections in mice

Smee, Donald F, Dagley, Ashley, Tarbet, EB

Journal:

Antiviral Chemistry & Chemotherapy

Year:

2017

Language:

english

File:

PDF, 241 KB

english, 2017

27

Antiviral Activities of Tragacanthin Polysaccharides on Punta Toro Virus Infections in Mice

Smee, Donald F., Sidwell, Robert W., Huffman, John H., Huggins, John W., Kende, Meir, Verbiscar, Anthony J.

Journal:

Year:

1996

Language:

english

File:

PDF, 831 KB

english, 1996

28

Treatment of oseltamivir-resistant influenza A (H1N1) virus infections in mice with antiviral agents

Donald F. Smee, Justin G. Julander, E. Bart Tarbet, Matthew Gross, Jack Nguyen

Journal:

Antiviral Research

Year:

2012

Language:

english

File:

PDF, 660 KB

english, 2012

29

Maternal infection leads to abnormal gene regulation and brain atrophy in mouse offspring: Implications for genesis of neurodevelopmental disorders

S. Hossein Fatemi, Teri J. Reutiman, Timothy D. Folsom, Hao Huang, Kenichi Oishi, Susumu Mori, Donald F. Smee, David A. Pearce, Christine Winter, Reinhard Sohr, Georg Juckel

Journal:

Schizophrenia Research

Year:

2008

Language:

english

File:

PDF, 1.26 MB

english, 2008

30

A recombinant, infectious human parainfluenza virus type 3 expressing the enhanced green fluorescent protein for use in high-throughput antiviral assays

Jason P. Roth, Joseph K.-K. Li, Donald F. Smee, John D. Morrey, Dale L. Barnard

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 496 KB

english, 2009

31

Combination of Neuraminidase Inhibitors with T-705 for Treating Influenza Virus Infections in Cell Culture and in Mice

Donald Smee, Min-Hui Wong, Kevin Bailey, John Morrey, Masako Maekawa, Kazumi Takahashi, Yousuke Furuta

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 68 KB

english, 2009

32

Metabolism of ganciclovir and cidofovir in cells infected with drug-resistant and wild-type strains of murine cytomegalovirus

Kevin M. Okleberry, Reed P. Warren, Donald F. Smee

Journal:

Antiviral Research

Year:

1997

Language:

english

File:

PDF, 624 KB

english, 1997

33

Primary immune system effects of the orally administered cyclopentane neuraminidase inhibitor RWJ-270201 in influenza virus-infected mice

Robert W Sidwell, Donald F Smee, Kevin W Bailey, Roger A Burger

Journal:

International Immunopharmacology

Year:

2001

Language:

english

File:

PDF, 106 KB

english, 2001

34

Nucleoside and nucleotide modulation of genetic expression — A new approach to chemotherapy

Roland K. Robins, Emmanuel Ojo-Amaize, Zahra Parandoosh, Howard B. Cottam, Steven S. Matsumoto, Ganapathi R. Revankar, Donald F. Smee, James M. Fujitaki, Randall C. Willis, Boanerges Rubalcava, L. Dee

Journal:

Advances in Enzyme Regulation

Year:

1989

Language:

english

File:

PDF, 1.22 MB

english, 1989

35

Treatment of lethal pichinde virus infections in weanling LVG/Lak hamsters with ribavirin, ribamidine, selenazofurin, and ampligen

Donald F. Smee, John Gilbert, Judy A. Leonhardt, Bill B. Barnett, John H. Huggins, Robert W. Sidwell

Journal:

Antiviral Research

Year:

1993

Language:

english

File:

PDF, 760 KB

english, 1993

36

p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression

Aston, Nicola M., Bamborough, Paul, Buckton, Jacqueline B., Edwards, Christopher D., Holmes, Duncan S., Jones, Katherine L., Patel, Vipulkumar K., Smee, Penny A., Somers, Donald O., Vitulli, Giovanni,

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.37 MB

english, 2009

37

Activity of Isatine-Sulfadimidine Derivatives against 2009 Pandemic H1N1 Influenza Virus in Cell Culture

Selvam, Periyasamy, Chandramohan, Markandavel, Hurst, Brett L, Smee, Donald F

Journal:

Antiviral Chemistry & Chemotherapy

Year:

2010

Language:

english

File:

PDF, 168 KB

english, 2010

38

Interaction of 9-(1,3-dihydroxy-2-propoxymethyl)guanine with cytosol and mitochondrial deoxyguanosine kinases: possible role in anti-cytomegalovirus activity

Journal:

Molecular and Cellular Biochemistry

Year:

1985

Language:

english

File:

PDF, 504 KB

english, 1985

39

Efficacy of 5-Halogenated 2′-Deoxyuridines on Vaccinia Virus Thymidine Kinase Positive and Negative Strains, and Influence of Cell Type on Antiviral Potency

Donald Smee, Daniel Humphreys, Brett Hurst, Robert Sidwell

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 49 KB

english, 2007

40

Effect of T-705 treatment on western equine encephalitis in a mouse model

Justin G. Julander, Donald F. Smee, John D. Morrey, Yousuke Furuta

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 159 KB

english, 2009

41

In vitro and in vivo activities of phosphate derivatives of 9-(1,3-dihydroxy-2-propoxymethyl)-guanine against cytomegaloviruses

Arit E. Duke, Donald F. Smee, Marlene Chernow, Richard Boehme, Thomas R. Matthews

Journal:

Antiviral Research

Year:

1986

Language:

english

File:

PDF, 471 KB

english, 1986

42

Synthesis and antiherpes simplex virus activity of 9-[(1,3-dihydroxy-2-propylthio)methyl]guanine

McGee, Danny P. C., Martin, John C., Smee, Donald F., Matthews, Thomas R., Verheyden, Julien P. H.

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 566 KB

english, 1985

43

Biological Response Modifiers in Combination with Antivirals against Experimentally-Induced Virus Infections

Sidwell, Robert W, Huffman, John H, Smee, Donald F, Gilbert, John, Robins, Roland K, Kende, Meir, Huggins, John

Journal:

Canadian Journal of Infectious Diseases

Year:

1992

Language:

english

File:

PDF, 3.77 MB

english, 1992

44

Efficacy of orally administered T-705 pyrazine analog on lethal West Nile virus infection in rodents

John D. Morrey, Brandon S. Taro, Venkatraman Siddharthan, Hong Wang, Donald F. Smee, Andrew J. Christensen, Yousuke Furuta

Journal:

Antiviral Research

Year:

2008

Language:

english

File:

PDF, 492 KB

english, 2008

45

Potential Role of Immunomodulators for Treatment of Phlebovirus Infections of Animals

ROBERT W. SIDWELL, JOHN H. HUFFMAN, DONALD F. SMEE, JOHN GILBERT, ANN GESSAMAN, AKO PEASE, REED P. WARREN, JOHN HUGGINS, MEIR KENDE

Journal:

Annals of the New York Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 533 KB

english, 1992

46

Antitumor and antiviral activity of synthetic .alpha.- and .beta.-ribonucleosides of certain substituted pyrimido[5,4-d]pyrimidines: a new synthetic strategy for exocyclic aminonucleosides

Sanghvi, Yogesh S., Larson, Steven B., Matsumoto, Steven S., Nord, L. Dee, Smee, Donald F., Willis, Randall C., Avery, Thomas L., Robins, Roland K., Revankar, Ganapathi R.

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 1.25 MB

english, 1989

47

Analysis of the in vitro antiviral activity of certain ribonucleosides against parainfluenza virus using a novel computer aided receptor modeling procedure

Ghose, Arup K., Crippen, Gordon M., Revankar, Ganapathi R., McKernan, Patricia A., Smee, Donald F., Robins, Roland K.

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 2.81 MB

english, 1989

48

Activities of oseltamivir and ribavirin used alone and in combination against infections in mice with recent isolates of influenza A (H1N1) and B viruses

Smee, Donald F., Wong, Min H., Bailey, Kevin W., Sidwell, Robert W.

Journal:

Antiviral Chemistry & Chemotherapy

Year:

2006

Language:

english

File:

PDF, 510 KB

english, 2006

49

Combination Treatment of Influenza A Virus Infections in Cell Culture and in Mice with the Cyclopentane Neuraminidase Inhibitor RWJ-270201 and Ribavirin

Smee, Donald F., Bailey, Kevin W., Morrison, Ann C., Sidwell, Robert W.

Journal:

Year:

2002

Language:

english

File:

PDF, 152 KB

english, 2002

50

Strain-dependent disease and response to favipiravir treatment in mice infected with Chikungunya virus

Julander, Justin G., Dagley, Ashley, Gebre, Makda, Komeno, Takashi, Nakajima, Nozomi, Smee, Donald F., Furuta, Yousuke

Journal:

Antiviral Research

Year:

2020

File:

PDF, 6.44 MB

2020

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